Neither your address nor the recipient's address will be used for any other purpose. This research was funded by GlycoNet and conducted in collaboration with a post-doctoral fellow, Tianlin Guo, and a graduate student, Radhika Chakraberty, working at the U of A. Increased exercise, cessation of smoking and a healthy diet help in addition to certain supplements. Atherosclerosis -- or hardening of the arteries -- is the leading cause of heart attacks, strokes, and peripheral vascular disease. "It was exciting to see that this project is proceeding to the next phase, which is one step closer to clinical application," said Warren Wakarchuk, professor in the Department of Biological Sciences and scientific director of GlycoNet. Plaque definition is - an ornamental brooch; especially : the badge of an honorary order. Plaque buildup causes coronary artery disease, carotid artery disease and peripheral artery disease. Daily science news on research developments and the latest scientific innovations, The latest engineering, electronics and technology advances, The most comprehensive sci-tech news coverage on the web. The content is provided for information purposes only. part may be reproduced without the written permission. You can unsubscribe at any time and we'll never share your details to third parties. The researchers examined the role of glycosylation of circulating lipid particles in the blood in atherosclerosis. This document is subject to copyright. New and more effective treatments are still needed, Cairo explained. "We identified a new mechanism underlying atherosclerosis," explained Chris Cairo, professor in the Department of Chemistry and co-lead author of the new study. Scientists identify drugs with potential to stop plaque buildup in arteries. Taking vitamin E supplements may provide help. . This site uses cookies to assist with navigation, analyse your use of our services, and provide content from third parties. Your opinions are important to us. Science X Daily and the Weekly Email Newsletter are free features that allow you to receive your favorite sci-tech news updates in your email inbox, Mid-life cardiovascular disease prevention may protect against later dementia, Neural mechanism that senses body position in space is present soon after birth, Relationship between type 1 diabetes, interferon response and viral infection is first step toward preventive therapies, Study finds that mPOA neurons mediate stress-induced anxiety and parental behavior in mice, SPARC: Protein responsible for tendon strength and resilience isolated in new study, Mathematical model of SARS-CoV-2 UK variant suggests it could be 43–90% more transmissible. Increasing the amount of these oils prevents plaque buildup and may even reduce it. and Terms of Use. Apart from any fair dealing for the purpose of private study or research, no The researchers identified a new mechanism responsible for the buildup of plaque on artery walls, a process known as atherosclerosis. or, by University of Alberta. Using inhibitors developed in our lab, we found that this could be a new strategy for therapeutics in cardiovascular disease.". Your feedback will go directly to Science X editors. Inflammation may promote the growth of plaques, loosen plaque in your arteries and trigger blood clots — the primary cause of heart attacks and strokes.” When a blood clot blocks an artery to the heart, you have a heart attack . The arteries often respond to the buildup by producing another secretion that adds to the clogging. Click here to sign in with Mohsen Meydani in his article, "Vitamin E and Atherosclerosis: Beyond Prevention of LDL Oxidation" published in the "Journal of Nutrition" 2001, says while most studies show vitamin E is effective in prevention of plaque buildup in the arteries, there are contradictory results whether vitamin E reduces existing plaque. Plaque is an accumulation of calcium cholesterol, fat, cellular waste and the blood clotting material fibrin, which sticks to the walls of the arteries. The researchers identified a new mechanism responsible for the buildup of plaque on artery walls, a process known as atherosclerosis. The researchers looked at LDL particles before and after removal of a specific glycan residue, known as sialic acid. How to Improve Kidney Function With Supplements. Plaque then slowly builds up and hardens in the arteries, causing them to narrow. By using our site, you acknowledge that you have read and understand our Privacy Policy If you have heavy amounts of plaque in your arteries, you need to both remove the existing plaque and prevent more from forming. Cairo and Pshezhetsky are both network investigators with GlycoNet, a pan-Canadian Network Centre of Excellence of more than 170 glycomics researchers, centered at the U of A. Learn more about causes, risk factors, screening and prevention, signs and symptoms, diagnoses, and treatments for atherosclerosis, and how to participate in clinical trials.
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